International cruises are one of the most convenient and safest ways to visit exotic locations, but like any form of travel, cruising the Panama Canal does come with some potential risks. According to the most recent U.S. Department of State Travel Advisory, Panama is considered a Level 1 destination, meaning that travelers should exercise normal precautions during their trip. However, there are some regions that authorities have identified as high risk, including parts of the Mosquito Gulf and the Darién region. The good news is that cruise lines do not make stops in these areas, but passengers should still pay attention to their surrounding both on and off the ship. Here are four safety tips to keep in mind before you embark on a Panama Canal cruise: